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Heart Rate
Variability
Heart rate variability provides a non-invasive means
of quantifying cardiac autonomic activity, and has
widespread application in clinical medicine1.
Assessment of Risk After Acute MI
Depressed HRV is a powerful predictor of mortality and
of arrhythmic complications in patients after acute MI2.
Risk stratification is designed for early identification
of the patients at high risk of complications. In all
cases, definitive therapy must be provided before the
development of re-infarction or sudden death1.
Assessment of Diabetic Neuropathy
Uraemia and diabetes can cause severe autonomic
dysfunction that can be responsible for several
disabling symptoms and sudden cardiac death1. A
reduction in HRV time-domain parameters predicts a
negative prognostic value but also precedes clinical
expression of autonomic neuropathy. This early
subclinical detection of autonomic dysfunction is
important for risk stratification and subsequent
management2.
Hypertension Several structural and functional alterations of the
cardiovascular system that are frequently found in
hypertensive individuals may increase the cardiovascular
risk beyond that induced by blood pressure alone1.
Patients with LVH have three times as many
cardiovascular events as those that do not. There is a
close association between HRV and left ventricular mass
index suggesting that deranged autonomic function may be
a cause of cardiovascular events in patients with
established hypertension1.
Elderly The Framingham Heart Study found that HRV was associated
with all-cause mortality and provided prognosis beyond
that provided by the evaluation of traditional
cardiovascular risk factors1.
Chronic
Heart Failure There is a close correlation between measurements of HRV
and functional status of heart failure patients. This
makes the method a potentially useful tool for further
classifying patients1. HRV may also provide an accurate
means of assessing the value of various drug
interventions in such patients1. The
SphygmoCor HRV System utilises a 3-lead ECG to
non-invasively provide an assessment of sympathetic and
para-sympathetic autonomic function in both the time and
frequency domains. The SphygmoCor HRV System can perform these
calculations in three different modes:
1. During stable supine resting
2. After Valsalva manoeuvre
3. After Standing manoeuvre This simple to use, doctor’s office system provides a
comprehensive assessment of heart rate variability and
autonomic function.
References
1. Kamen P. (1996) Heart Rate
Variability. Australian Family Physician Vol 25,
7:1087-1095
2. Task force of the European
Society of Cardiology (1996) Heart Rate Variability,
Standards of measurement, physiology interpretation, and
clinical use. Circulation 93:1043-1065
* Regulatory Status
SphygmoCor Heart Rate Variability has TGA approval for
sale within Australia. CE Mark approval
is pending.
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Assessment of Risk After Acute MI